184756

4-Phenyl-1-butanol

99%

• Linear Formula: C₆H₅(CH₂)₄OH
• CAS Number: 3360-41-6
• Molecular Weight: 150.22
• Beilstein/REAXYS Number: 2042122
• EC Number: 222-128-8
• MDL number: MFCD00002971
• UNSPSC Code: 12352100
• PubChem Substance ID: 24851129
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 99%
• form: liquid
• refractive index: n20/D 1.521 (lit.)
• bp: 140-142 °C/14 mmHg (lit.)
• density: 0.984 g/mL at 20 °C (lit.)
• functional group: hydroxyl; phenyl
• SMILES string: OCCCCc1ccccc1
• InChI: 1S/C10H14O/c11-9-5-4-8-10-6-2-1-3-7-10/h1-3,6-7,11H,4-5,8-9H2
• InChI key: LDZLXQFDGRCELX-UHFFFAOYSA-N

Description

General description

4-Phenyl-1-butanol is oxidized by ceric ammonium nitrate in acetonitrile to afford 2-phenyltetrahydrofuran. It undergoes cyclization in presence of phosphoric acid at high temperature to yield tetralin.

Application

4-Phenyl-1-butanol was used in synthesis of NK105, a paclitaxel-incorporating micellar nanoparticle formulation.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 230.0 °F - closed cup
• flash_point_c: 110 °C - closed cup
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)