188549

2-Mercaptopyridine N-oxide

99%

• Synonym(s): 2-Pyridinethiol-1-oxide, Pyrithione
• Empirical Formula (Hill Notation): C₅H₅NOS
• CAS Number: 1121-31-9
• Molecular Weight: 127.16
• Beilstein/REAXYS Number: 109936
• EC Number: 214-329-4
• MDL number: MFCD00006196
• UNSPSC Code: 12352100
• PubChem Substance ID: 24851166
• NACRES: NA.22

Properties

• assay: 99%
• mp: 69-72 °C (lit.)
• SMILES string: [O-][n+]1ccccc1S
• InChI: 1S/C5H5NOS/c7-6-4-2-1-3-5(6)8/h1-4,8H
• InChI key: FGVVTMRZYROCTH-UHFFFAOYSA-N

Description

General description

2-Mercaptopyridine N-oxide forms complexes on reaction with palladium chloride. It inhibits NADH-fumarate reductase purified from Trypanosoma cruzi. It is precursor to O-acyl thiohydroxamates. It ligates to metals to form biologically active complexes.

Application

2-Mercaptopyridine N-oxide was used to investigate the mechanism of photodegradation of mercaptopyridine-N-oxide biocides. It was used in ratiometric fluorescence imaging of intracellular zinc ions in mammalian cultures.

Precursor to O-acyl thiohydroxamates. Ligates to metals to form biologically active complexes.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H315,H319,H335
• pcodes: P261 - P264 - P271 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves