196487

4-Biphenylacetic acid

98%

• Linear Formula: C₆H₅C₆H₄CH₂CO₂H
• CAS Number: 5728-52-9
• Molecular Weight: 212.24
• EC Number: 227-233-2
• MDL number: MFCD00004351
• UNSPSC Code: 12352100
• PubChem Substance ID: 24851763
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 98%
• mp: 159-160 °C (lit.)
• solubility: DMSO: soluble 50 mg/mL, clear, colorless to yellow
• SMILES string: OC(=O)Cc1ccc(cc1)-c2ccccc2
• InChI: 1S/C14H12O2/c15-14(16)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16)
• InChI key: QRZAKQDHEVVFRX-UHFFFAOYSA-N
• Gene Information: human ... BAD(572)

Description

General description

4-Biphenylacetic acid is a potential non-steroidal antiinflammatory agent and forms solid inclusion complex with β-cyclodextrin. 4-Biphenylacetic acid on interaction with quinolone antibacterial agents induces functional blockade of the γ-aminobutyric acid receptors.

Application

4-Biphenylacetic acid was used in the synthesis of gastrosparing non-steroidal antiinflammatory drug.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301 + H331,H315,H319,H335
• pcodes: P261 - P264 - P301 + P310 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges