241512

Tetrabutylammonium fluoride hydrate

98%

• Synonym(s): TBAF
• Linear Formula: [CH₃(CH₂)₃]₄NF·xH₂O
• CAS Number: 22206-57-1
• Molecular Weight: 261.46 (anhydrous basis)
• MDL number: MFCD00149980
• UNSPSC Code: 12352116
• PubChem Substance ID: 24854487
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: 98%
• form: solid
• mp: 62-63 °C (lit.)
• functional group: amine
• SMILES string: O.[F-].CCCC[N+](CCCC)(CCCC)CCCC
• InChI: 1S/C16H36N.FH.H2O/c1-5-9-13-17(14-10-6-2,15-11-7-3)16-12-8-4;;/h5-16H2,1-4H3;1H;1H2/q+1;;/p-1
• InChI key: UQCWXKSHRQJGPH-UHFFFAOYSA-M

Description

General description

Tetrabutylammonium fluoride hydrate is known to be a source of F⁻ anion, used in nucleophilic fluorination reactions.

Application

Reactant for preparation of:

• Double clathrate hydrates at high pressures
• Cellulose ethers
• Terminal olefins via dehydrohalogenation reactions
• Neutral and zwitterionic 3-carboranyl thymidine analogues for boron neutron capture therapy

Tetrabutylammonium fluoride hydrate can be used:

• To prepare 2,7-diethynyl-9-propyl-9H-carbazole, which is a key intermediate for the synthesis of calix[4]arene−carbazole polymers.
• As an anion source in the study of selective detection of F⁻ by anion receptor viz Schiff base.
• To prepare terminal olefins from primary alkyl iodides

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges