265128

5-Fluoroindole-2-carboxylic acid

99%

• Empirical Formula (Hill Notation): C₉H₆FNO₂
• CAS Number: 399-76-8
• Molecular Weight: 179.15
• EC Number: 206-919-5
• MDL number: MFCD00005612
• UNSPSC Code: 12352100
• PubChem Substance ID: 24277978
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 99%
• form: solid
• mp: 259 °C (dec.) (lit.)
• functional group: carboxylic acid; fluoro
• SMILES string: OC(=O)c1cc2cc(F)ccc2[nH]1
• InChI: 1S/C9H6FNO2/c10-6-1-2-7-5(3-6)4-8(11-7)9(12)13/h1-4,11H,(H,12,13)
• InChI key: WTXBRZCVLDTWLP-UHFFFAOYSA-N

Description

General description

5-Fluoroindole-2-carboxylic acid is an antagonist of the glycine site within the NMDA (N-methyl-D-aspartate) receptor complex.

Application

Reactant for the synthesis of:

• Fungicidal agents
• Antitumor agents
• 2,3-dioxygenase (IDO) inhibitors
• Factor Xa inhibitors
• Enantioselective D3 receptor antagonists
• Ligands for hFPRL1 (or ALXR) receptor in inflammation
• Antibacterial agents
• Inhibitors of hepatitis C virus NS3·4A protease

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves