27395

1,4-Cineole

technical, mixture of isomers, ≥85% (GC)

• Synonym(s): 1-Isopropyl-4-methyl-7-oxabicyclo[2.2.1]heptane
• Empirical Formula (Hill Notation): C₁₀H₁₈O
• CAS Number: 470-67-7
• Molecular Weight: 154.25
• Beilstein/REAXYS Number: 104974
• EC Number: 207-428-9
• MDL number: MFCD00209502
• UNSPSC Code: 12352100
• PubChem Substance ID: 57648243
• NACRES: NA.22

Properties

• Quality Level: 100
• grade: technical
• assay: ≥85% (GC)
• form: liquid
• composition: 1,4-cineol, ~75% ; 1,8-cineol, ~15%
• refractive index: n20/D 1.445 (lit.); n20/D 1.447
• bp: 65 °C/16 mmHg (lit.)
• mp: −46 °C (lit.)
• density: 0.887 g/mL at 25 °C (lit.)
• functional group: ether
• SMILES string: CC(C)C12CCC(C)(CC1)O2
• InChI: 1S/C10H18O/c1-8(2)10-6-4-9(3,11-10)5-7-10/h8H,4-7H2,1-3H3/t9-,10+
• InChI key: RFFOTVCVTJUTAD-AOOOYVTPSA-N

Description

General description

1,4-Cineole is present in eucalyptus oil. It activated both human TRPA1 (a sensor of noxious cold) and human TRPM 8 (a thermosensitive receptor). It is a natural monoterpene that inhibits plant growth.

Safety Information

• pictograms: GHS02
• signalword: Warning
• hcodes: H226
• pcodes: P210 - P233 - P240 - P241 - P242 - P243
• Hazard Classifications: Flam. Liq. 3
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 2
• flash_point_f: 116.6 °F - closed cup
• flash_point_c: 47 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter