275271

3,7-Dihydroxy-2-naphthoic acid

95%

• Linear Formula: (HO)₂C₁₀H₅CO₂H
• CAS Number: 83511-07-3
• Molecular Weight: 204.18
• Beilstein/REAXYS Number: 3288005
• MDL number: MFCD00010253
• UNSPSC Code: 12352100
• PubChem Substance ID: 24856639
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: 95%
• form: powder
• mp: 265 °C±10 °C (dec.) (lit.)
• SMILES string: OC(=O)c1cc2cc(O)ccc2cc1O
• InChI: 1S/C11H8O4/c12-8-2-1-6-5-10(13)9(11(14)15)4-7(6)3-8/h1-5,12-13H,(H,14,15)
• InChI key: QMWOUSYSNFCKAZ-UHFFFAOYSA-N

Description

General description

3,7-Dihydroxy-2-naphthoic acid served as a substrate for the enzyme NcsB₁ (an O-methyltransferase involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin) in the NcsB₁-catalyzed O-methylation of 2,7-dihydroxy-5-methyl-1-naphthoic acid.

Application

3,7-Dihydroxy-2-naphthoic acid was used in the synthesis of 3-hydroxy-7-methoxy-2-naphthoic acid.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H319
• pcodes: P264 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves