281077

Trimethyloxonium tetrafluoroborate

95%

• Synonym(s): Trimethyloxonium fluoroborate
• Linear Formula: (CH₃)₃O(BF₄)
• CAS Number: 420-37-1
• Molecular Weight: 147.91
• Beilstein/REAXYS Number: 3597303
• EC Number: 206-994-4
• MDL number: MFCD00011798
• UNSPSC Code: 12352107
• PubChem Substance ID: 24856967
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: 95%
• form: solid
• functional group: ether
• storage temp.: −20°C
• SMILES string: C[O+](C)C.F[B-](F)(F)F
• InChI: 1S/C3H9O.BF4/c1-4(2)3;2-1(3,4)5/h1-3H3;/q+1;-1
• InChI key: CZVZBKHWOFJNCR-UHFFFAOYSA-N

Description

General description

Trimethyloxonium tetrafluoroborate can be used as a methylating agent for the methylation of hydroxyl/carboxyl functional groups. It is capable of methylating polyfunctional carboxylic acids. It is also used as a catalyst for the polymerization of cyclic sulfides and ethers.

Application

Reagent for the methylation of hydroxyl groups recently used in a complex, multistep synthesis directed towards spirastrellolide, a marine natural product.

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Skin Corr. 1B
• supp_hazards: EUH014
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges