288144

Tricarbonyldichlororuthenium(II) dimer

• Synonym(s): CORM-2
• Linear Formula: [Ru(CO)₃Cl₂]₂
• CAS Number: 22594-69-0
• Molecular Weight: 512.01
• MDL number: MFCD00011528
• UNSPSC Code: 12161600
• PubChem Substance ID: 24857320
• NACRES: NA.22

Properties

• Quality Level: 100
• reaction suitability: core: ruthenium; reagent type: catalyst
• SMILES string: [C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].Cl[Ru]Cl.Cl[Ru]Cl
• InChI: 1S/6CO.4ClH.2Ru/c6*1-2;;;;;;/h;;;;;;4*1H;;/q;;;;;;;;;;2*+2/p-4
• InChI key: JYHHJVKGDCZCCL-UHFFFAOYSA-J

Description

Application

Carbon monoxide-releasing molecule used for pharamological studies including:

• Enhancement of coagulation and attenuation of vulnerability to fibrinolysis
• Investigations of P2X4 as a possible target
• Possible modification of thrombus growth or disintegration
• Enhances fibrinogen as a substrate for thrombin
• Regulation of ion transport by gasotransmitters

Used as a CO donor for reactive oxygen species mediated bacterial killing

Tricarbonyldichlororuthenium(II) dimer can be used in the deuteration reaction for labeling secondary amines. It can also be used for the synthesis of racemization catalysts by reacting with cyclopenta[l]phenanthrenyl and cyclopenta[a]acenaphthylenyl ligands.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H312 + H332,H315,H319,H335
• pcodes: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves