300977

(R)-4-Benzyl-2-oxazolidinone

99%

• Empirical Formula (Hill Notation): C₁₀H₁₁NO₂
• CAS Number: 102029-44-7
• Molecular Weight: 177.20
• Beilstein/REAXYS Number: 4782551
• MDL number: MFCD00010846
• UNSPSC Code: 12352005
• PubChem Substance ID: 24858151
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 99%
• form: powder
• optical activity: [α]18/D +64°, c = 1 in chloroform
• mp: 88-90 °C
• SMILES string: O=C1N[C@@H](CO1)Cc2ccccc2
• InChI: 1S/C10H11NO2/c12-10-11-9(7-13-10)6-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,11,12)/t9-/m1/s1
• InChI key: OJOFMLDBXPDXLQ-SECBINFHSA-N

Description

Application

(R)-4-Benzyl-2-oxazolidinone may be used as a starting material in the synthesis of enantiopure carbocyclic nucleosides. It may also be used as a chiral auxiliary in the enantioselective synthesis of (2R,2′S)-erythro-methylphenidate.

Used in the synthesis of HIV protease inhibitors.

Versatile chiral auxiliary for asymmetric synthesis. For a recent review, see Aldrichimica Acta.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)