302481

4-Pentyn-1-ol

97%

• Synonym(s): (3-Hydroxypropyl)acetylene, 1-Hydroxy-4-pentyne, 1-Pentyn-5-ol, 5-Hydroxy-1-pentyne, Pent-4-yn-1-ol, Pent-4-yne-1-ol, Pentyne alcohol
• Linear Formula: HC≡CCH₂CH₂CH₂OH
• CAS Number: 5390-04-5
• Molecular Weight: 84.12
• Beilstein/REAXYS Number: 1736712
• EC Number: 226-383-6
• MDL number: MFCD00002974
• UNSPSC Code: 12352100
• PubChem Substance ID: 24858256
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 97%
• form: liquid
• refractive index: n20/D 1.445 (lit.)
• bp: 154-155 °C (lit.)
• density: 0.904 g/mL at 25 °C (lit.)
• functional group: hydroxyl
• SMILES string: OCCCC#C
• InChI: 1S/C5H8O/c1-2-3-4-5-6/h1,6H,3-5H2
• InChI key: CRWVOXFUXPYTRK-UHFFFAOYSA-N

Description

General description

Mechanism of (THF)W(CO)₅-promoted endo- and exo-cycloisomerization of 4-pentyn-1-ol was studied.

Application

4-Pentyn-1-ol was used in preparation of 3-pent-4-ynyloxy phthalonitrile. It was also used as starting reagent in stereoselective total synthesis of antimicrobial marine metabolites, ieodomycin A and B.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 143.6 °F - closed cup
• flash_point_c: 62 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter