303410

Sodium butyrate

98%

• Synonym(s): Butyric acid sodium salt
• Linear Formula: CH₃CH₂CH₂COONa
• CAS Number: 156-54-7
• Molecular Weight: 110.09
• Beilstein/REAXYS Number: 3629439
• EC Number: 205-857-6
• MDL number: MFCD00002816
• UNSPSC Code: 12352100
• PubChem Substance ID: 24858121
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: 98%
• form: powder
• mp: 250-253 °C (lit.)
• SMILES string: [Na+].CCCC([O-])=O
• InChI: 1S/C4H8O2.Na/c1-2-3-4(5)6;/h2-3H2,1H3,(H,5,6);/q;+1/p-1
• InChI key: MFBOGIVSZKQAPD-UHFFFAOYSA-M
• Gene Information: mouse ... ENSMUSG00000061062(15181)

Description

General description

Sodium butyrate is the sodium salt form of butyric acid. It is a a natural compound known to inhibit tumor-cell growth and its biological activity in a human breast-cancer cell line (MCF7) was investigated. Sodium butyrate may be an effective drug for the treatment of human spinal muscular atrophy patients.

Sodium butyrate, an aliphatic sodium salt, serves as an acylating reagent for phenols.

Application

Sodium butyrate can be used as a reactant to prepare butanal by reduction using 9-borabicyclo[3.3.1]nonane (9-BBN) in THF. It is also converted into butanal borane and pyridinium chlorochromate by the reductive oxidation reaction. Sodium butyrate is reacted with different alcohols to yield esters by Mitsunobu reaction using ionic liquid-based chloroiminium reagent.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319
• pcodes: P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves