333018

Choline hydroxide solution

45 wt. % in methanol

• Synonym(s): (2-Hydroxyethyl)trimethylammonium hydroxide, (beta-Hydroxyethyl)trimethylammonium hydroxide, 2-Hydroxy-N,N,N-trimethylethanaminium hydroxide
• Linear Formula: HOCH₂CH₂N(CH₃)₃OH
• CAS Number: 123-41-1
• Molecular Weight: 121.18
• MDL number: MFCD00002831
• UNSPSC Code: 12352000
• PubChem Substance ID: 24860096
• NACRES: NA.22

Properties

• form: liquid
• Quality Level: 200
• contains: 0.5% paraformaldehyde as stabilizer
• concentration: 45 wt. % in methanol
• refractive index: n20/D 1.4186
• density: 0.945 g/mL at 25 °C
• functional group: amine; hydroxyl
• SMILES string: [OH-].C[N+](C)(C)CCO
• InChI: 1S/C5H14NO.H2O/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H2/q+1;/p-1
• InChI key: KIZQNNOULOCVDM-UHFFFAOYSA-M

Description

General description

Choline hydroxide solution, also known as choline base, is a strong organic base that can be used in the chemical industry as a solvent, catalyst, and corrosion inhibitor. It can also be used as a stabilizer for quaternary ammonium compounds and as a phase transfer agent in organic synthesis.

Application

Choline hydroxide solution can be used as a catalyst in the efficient conversion of CO₂ and 2-aminobenzonitriles to quinazoline-2,4(1H,3H)-dione derivatives.

Safety Information

• pictograms: GHS02,GHS06,GHS08,GHS05
• signalword: Danger
• hcodes: H226,H301 + H311 + H331,H314,H350,H370
• pcodes: P202 - P210 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A - STOT SE 1
• target_organs: Eyes,Central nervous system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 2
• flash_point_f: 73.4 °F - closed cup
• flash_point_c: 23 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter