335975

(+)-1-(9-Fluorenyl)ethyl chloroformate solution

18 mM in acetone

• Synonym(s): (+)-FLEC solution
• Empirical Formula (Hill Notation): C₁₆H₁₃ClO₂
• CAS Number: 107474-79-3
• Molecular Weight: 272.73
• MDL number: MFCD00043429
• UNSPSC Code: 12352005
• PubChem Substance ID: 24860354
• NACRES: NA.22

Properties

• grade: derivatization grade ((chiral))
• Quality Level: 100
• vapor density: 2 (vs air)
• vapor pressure: 180 mmHg ( 20 °C)
• form: liquid
• concentration: 18 mM in acetone
• refractive index: n20/D 1.3602
• density: 0.79 g/mL at 25 °C
• functional group: chloro
• storage temp.: 2-8°C

Description

General description

(+)-1-(9-Fluorenyl)ethyl chloroformate is a highly fluorescent compound1 commonly used as a chiral derivatizing agent for the separation of racemates prior to reversed-phase HPLC analysis.[1][2]

Application

• Chiral analysis of β-methylamino alanine (BMAA) enantiomers: Details the use of (+)-1-(9-fluorenyl)-ethyl chloroformate (FLEC) for derivatization followed by LC-MS/MS analysis, improving the understanding of amino acids′ stereochemistry (Zurita et al., 2019).
• Enantioselective micellar electrokinetic chromatography of dl‐amino acids: Utilizes (+)-1-(9-fluorenyl)ethyl chloroformate derivatization combined with UV-induced fluorescence detection to analyze amino acids, enhancing analytical methodologies (Prior et al., 2018).

Safety Information

• pictograms: GHS02,GHS05,GHS07
• signalword: Danger
• hcodes: H225,H318,H336
• pcodes: P210 - P280 - P304 + P340 + P312 - P305 + P351 + P338 + P310 - P403 + P235
• Hazard Classifications: Eye Dam. 1 - Flam. Liq. 2 - STOT SE 3
• target_organs: Central nervous system
• supp_hazards: EUH066
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 1.4 °F
• flash_point_c: -17 °C