345504

2,4,6-Trichlorobenzoyl chloride

97%

• Synonym(s): 2,4,6-Trichlorobenzoyl chloride
• Linear Formula: Cl₃C₆H₂COCl
• CAS Number: 4136-95-2
• Molecular Weight: 243.90
• MDL number: MFCD00075323
• UNSPSC Code: 12352100
• PubChem Substance ID: 24861329
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: 97%
• form: liquid
• refractive index: n20/D 1.5754 (lit.)
• bp: 107-108 °C/6 mmHg (lit.)
• density: 1.561 g/mL at 25 °C (lit.)
• functional group: acyl chloride; chloro
• SMILES string: ClC(=O)c1c(Cl)cc(Cl)cc1Cl
• InChI: 1S/C7H2Cl4O/c8-3-1-4(9)6(7(11)12)5(10)2-3/h1-2H
• InChI key: OZGSEIVTQLXWRO-UHFFFAOYSA-N

Description

Application

2,4,6-Trichlorobenzoyl chloride may be used in the preparation of:

• γ-lactone and δ-lactone
• aliphatic aromatic anhydrides, required for the synthesis of amphiphilic hyaluronan
• mixed anhydride, required for the synthesis of angelate esters
• synthesis of both spongistatin 1 and spongistatin 2
• large-ring lactones in high yields.

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 235.4 °F - closed cup
• flash_point_c: 113 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter