346861

(S)-(−)-5-Hydroxymethyl-2(5H)-furanone

98%

• Empirical Formula (Hill Notation): C₅H₆O₃
• CAS Number: 78508-96-0
• Molecular Weight: 114.10
• Beilstein/REAXYS Number: 3537455
• MDL number: MFCD00075370
• UNSPSC Code: 12352005
• PubChem Substance ID: 24861447
• NACRES: NA.22

Properties

• assay: 98%
• optical activity: [α]20/D −144°, c = 1 in H₂O
• mp: 41-43 °C (lit.)
• functional group: ester; hydroxyl
• storage temp.: 2-8°C
• SMILES string: OC[C@H]1OC(=O)C=C1
• InChI: 1S/C5H6O3/c6-3-4-1-2-5(7)8-4/h1-2,4,6H,3H2/t4-/m0/s1
• InChI key: AWNLUIGMHSSXHB-BYPYZUCNSA-N

Description

Application

(S)-(−)-5-Hydroxymethyl-2(5H)-furanone can be used as a starting material in the preparation of:

• Partially saturated heterocycles via a diastereoselective ring chain formation.
• A natural product named (+)-muscarine.
• 3′-Ethynylthymidine as a possible antiviral agent.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: 235.4 °F - closed cup
• flash_point_c: 113 °C - closed cup
• ppe: Eyeshields, Gloves, type N95 (US)