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MilliporeSigma

347647

Sigma-Aldrich

5-Methyl-2-pyrazinecarboxylic acid

98%

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About This Item

Empirical Formula (Hill Notation):
C6H6N2O2
CAS Number:
Molecular Weight:
138.12
Beilstein/REAXYS Number:
116005
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Pricing and availability is not currently available.

Quality Level

assay

98%

mp

167-171 °C (lit.)

functional group

carboxylic acid

SMILES string

Cc1cnc(cn1)C(O)=O

InChI

1S/C6H6N2O2/c1-4-2-8-5(3-7-4)6(9)10/h2-3H,1H3,(H,9,10)

InChI key

RBYJWCRKFLGNDB-UHFFFAOYSA-N

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1 of 4

This Item
2713427150-U27172-U
feature

closure type green melamine solid-top cap, closure type screw top vial

feature

closure type green melamine solid-top cap, closure type screw top vial

feature

closure type green melamine solid-top cap, closure type screw top vial

feature

closure type green melamine solid-top cap, closure type screw top vial

volume

15 mL

volume

2 mL

volume

7 mL

volume

22 mL

fitting

thread for 18-400

fitting

thread for 8-425

fitting

thread for 15-425

fitting

thread for 20-400

material

F217/PTFE cap liner, clear glass vial, PTFE liner, green melamine resin cap (solid-top)

material

F217/PTFE cap liner, PTFE liner, clear glass vial (standard opening - 4.6 mm), green melamine resin cap (solid-top)

material

F217/PTFE cap liner, PTFE liner, clear glass vial, green melamine resin cap (solid-top)

material

F217/PTFE cap liner, PTFE liner, clear glass vial, green melamine resin cap (solid-top)

packaging

pkg of 100 ea

packaging

pkg of 100 ea

packaging

pkg of 100 ea

packaging

pkg of 100 ea

O.D. × H

21 mm × 70 mm

O.D. × H

-

O.D. × H

17 mm × 60 mm

O.D. × H

23 mm × 85 mm

General description

5-Methyl-2-pyrazinecarboxylic acid is a pyrazine derivative. Simultaneous membrane based solvent extraction (MBSE) and membrane based solvent stripping (MBSS) of 5-methyl-2-pyrazine carboxylic acid (MPCA) has been studied.[1] Mechanism of pertraction of MPCA through layered bulk liquid membranes has been studied.[2] MPCA reacts with Ln(NO3)3·6H2O and K4[W(CN)8]·2H2O to form unique three-dimensional network structure which contains open channels.[3]

Application

5-Methyl-2-pyrazinecarboxylic acid may be used in the preparation of novel europium(III) complexes, (5-methyl-2-pyrazinecarboxylato) (phenanthroline)europium(III).[4] It may be used in the synthesis of Ln-metal organic frameworks (MOFs).[5]

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Tau protein in cerebrospinal fluid: a biochemical marker for axonal degeneration in Alzheimer disease?
Blennow K, et al.
Molecular and Chemical Neuropathology, 26(3), 231-245 (1995)
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Over four decades ago, in vitro experiments showed that tau protein interacts with and stabilizes microtubules in a phosphorylation-dependent manner. This observation fueled the widespread hypotheses that these properties extend to living neurons and that reduced stability of microtubules represents
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The Journal of biological chemistry, 295(52), 18508-18523 (2020-11-01)
Synapse loss is associated with motor and cognitive decline in multiple neurodegenerative disorders, and the cellular redistribution of tau is related to synaptic impairment in tauopathies, such as Alzheimer's disease and frontotemporal dementia. Here, we examined the cellular distribution of

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