359475

Methyl 2-oxo-2H-pyran-3-carboxylate

98%

• Synonym(s): Methyl 2-pyrone-3-carboxylate
• Empirical Formula (Hill Notation): C₇H₆O₄
• CAS Number: 25991-27-9
• Molecular Weight: 154.12
• Beilstein/REAXYS Number: 1424749
• EC Number: 247-397-9
• MDL number: MFCD00075443
• UNSPSC Code: 12352100
• PubChem Substance ID: 24862080
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: 98%
• form: powder
• bp: 146-148 °C/0.75 mmHg (lit.)
• mp: 75-77 °C (lit.)
• functional group: ester
• SMILES string: COC(=O)C1=CC=COC1=O
• InChI: 1S/C7H6O4/c1-10-6(8)5-3-2-4-11-7(5)9/h2-4H,1H3
• InChI key: GJVZWOMUTYNUCE-UHFFFAOYSA-N

Description

General description

Methyl 2-oxo-2H-pyran-3-carboxylate is a cyclic α,β -unsaturated ketone. It activates caspases-3, -8 and -9 weakly in HL-60 cells.

Application

Methyl 2-oxo-2H-pyran-3-carboxylate is suitable reagent used to investigate the series of simple α,β-unsaturated carbonyl compounds for their cytotoxic profiles against oral human normal and tumor cells.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)