366463

Methyl nitroacetate

98%

• Linear Formula: NO₂CH₂COOCH₃
• CAS Number: 2483-57-0
• Molecular Weight: 119.08
• Beilstein/REAXYS Number: 1758670
• EC Number: 219-622-0
• MDL number: MFCD00075480
• UNSPSC Code: 12352100
• PubChem Substance ID: 24862657
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 98%
• form: liquid
• refractive index: n20/D 1.425 (lit.)
• bp: 195-198 °C (lit.)
• density: 1.294 g/mL at 25 °C (lit.)
• functional group: amine; ester; nitro
• SMILES string: COC(=O)C[N+]([O-])=O
• InChI: 1S/C3H5NO4/c1-8-3(5)2-4(6)7/h2H2,1H3
• InChI key: ALBSWLMUHHZLLR-UHFFFAOYSA-N

Description

Application

Methyl nitroacetate may be used:

• in the preparation of aromatic and heteroaromatic linear (E)-α-nitro-arylpentenoates
• to generate phenyliodonium ylide, used in the highly enantioselective and diastereoselective Cu(I)-catalyzed cyclopropanation of alkenes
• in the preparation of methyl (Z)-2-nitro-3-(4-nitrophenyl)-2-propenoate, via reaction with 4-nitrobenzylideneaniline

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 2
• flash_point_f: 221.0 °F - closed cup
• flash_point_c: 105 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter