380350

2-Bromo-5-fluorophenol

97%

• Linear Formula: BrC₆H₃(F)OH
• CAS Number: 147460-41-1
• Molecular Weight: 191.00
• MDL number: MFCD00040939
• UNSPSC Code: 12352100
• PubChem Substance ID: 24863735
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 97%
• form: liquid
• refractive index: n20/D 1.553 (lit.)
• density: 1.717 g/mL at 25 °C (lit.)
• functional group: bromo; fluoro
• SMILES string: Oc1cc(F)ccc1Br
• InChI: 1S/C6H4BrFO/c7-5-2-1-4(8)3-6(5)9/h1-3,9H
• InChI key: HUVAOAVBKOVPBZ-UHFFFAOYSA-N

Description

General description

2-Bromo-5-fluorophenol an aryl fluorinated building block.

Application

2-Bromo-5-fluorophenol may be used for the preparation of reaction intermediates required for the synthesis of polycyclic 5-HT₃ and 5-HT₄ antagonists.[1] It may be used for the the nucleophilic substitution of the 2,2′,4,4′-tetrabromodiphenyl iodonium chloride (iodyl salt).[2]

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 188.6 °F - closed cup
• flash_point_c: 87 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter