381055

2-Methyl-1-pyrroline

95%

• Empirical Formula (Hill Notation): C₅H₉N
• CAS Number: 872-32-2
• Molecular Weight: 83.13
• EC Number: 212-822-9
• MDL number: MFCD00128806
• UNSPSC Code: 12352100
• PubChem Substance ID: 24863786
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 95%
• refractive index: n20/D 1.444 (lit.)
• bp: 104-105 °C (lit.)
• density: 0.878 g/mL at 25 °C (lit.)
• SMILES string: CC1=NCCC1
• InChI: 1S/C5H9N/c1-5-3-2-4-6-5/h2-4H2,1H3
• InChI key: CTSZPNIMMLSKDV-UHFFFAOYSA-N

Description

General description

2-Methyl-1-pyrroline, a monocyclic imine, is a pyrroline derivative. It is a five-membered heterocyclic compound having various biological and pharmacological applications. It is formed during the Rh(I) complexes (containing N,N-donor ligands and N,P-donor ligand) immobilized on glassy carbon electrode surfaces catalyzed intramolecular hydroamination of 4-pentyn-1-amine. It reacts with with 2-oxopropanal to afford acetyl-1-pyrroline (AP).

Application

2-Methyl-1-pyrroline (2-MPN) may be used in the enantioselective enzymatic synthesis of (R)- and (S)-2-methylpyrroline in the presence of whole-cells catalysts isolated from Strptomyces sp. strains GF3587 and GF3546 respectively.

Safety Information

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H315,H319,H335
• pcodes: P210 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 51.8 °F - closed cup
• flash_point_c: 11 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter