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MilliporeSigma

382337

Sigma-Aldrich

(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol

98%

Synonym(s):

α,α-Diphenyl-D-prolinol, (R)-2-(Diphenylhydroxymethyl)pyrrolidine

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About This Item

Empirical Formula (Hill Notation):
C17H19NO
CAS Number:
Molecular Weight:
253.34
Beilstein/REAXYS Number:
4353363
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22

Pricing and availability is not currently available.

assay

98%

form

solid

optical activity

[α]20/D +69°, c = 3 in chloroform

mp

77-80 °C (lit.)

functional group

hydroxyl
phenyl

SMILES string

OC([C@H]1CCCN1)(c2ccccc2)c3ccccc3

InChI

1S/C17H19NO/c19-17(16-12-7-13-18-16,14-8-3-1-4-9-14)15-10-5-2-6-11-15/h1-6,8-11,16,18-19H,7,12-13H2/t16-/m1/s1

InChI key

OGCGXUGBDJGFFY-MRXNPFEDSA-N

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This Item
P09500005675377699
technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

environmental

application(s)

-

format

neat

format

neat

format

neat

format

-

Quality Level

300

Quality Level

-

Quality Level

100

Quality Level

200

grade

certified reference material, pharmaceutical secondary standard

grade

pharmaceutical primary standard

grade

analytical standard

grade

-

storage temp.

2-30°C

storage temp.

2-8°C

storage temp.

-

storage temp.

-

Application

Used to prepare the corresponding oxazaborolidines for the borane-mediated asymmetric reduction of ketones.[1]

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Maria Lauda Tomasi et al.
Oncotarget, 8(45), 78851-78869 (2017-11-08)
MicroRNA-34a (miR-34a) is down-regulated in colorectal cancers (CRC) and required for interleukin-6 (IL-6)-induced CRC metastasis. Mice lacking miR-34a developed more invasive cancer in a colitis-associated cancer model. In the same model, S-adenosylmethionine (SAMe) and methylthioadenosine (MTA) inhibited IL-6/STAT3 and lowered

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Utilize these Caco-2 cell based assay tools for screening small molecule drug compounds prior to clinical studies and submission to regulatory agencies.

Application note on Drug transport assays in a 96-well system using Millicell-96 System from Millipore.

We presents an article on The Role of Intestinal Efflux Transporters In Drug Absorption.

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