384275

2,3,5-Trichloropyridine

99%

• Empirical Formula (Hill Notation): C₅H₂Cl₃N
• CAS Number: 16063-70-0
• Molecular Weight: 182.44
• Beilstein/REAXYS Number: 119384
• EC Number: 407-270-2
• MDL number: MFCD00043007
• UNSPSC Code: 12352100
• PubChem Substance ID: 24863657
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: 99%
• bp: 219 °C (lit.)
• mp: 46-50 °C (lit.)
• functional group: chloro
• SMILES string: Clc1cnc(Cl)c(Cl)c1
• InChI: 1S/C5H2Cl3N/c6-3-1-4(7)5(8)9-2-3/h1-2H
• InChI key: CNLIIAKAAMFCJG-UHFFFAOYSA-N

Description

General description

Separation and migration behavior of 2,3,5-trichloropyridine has been studied by micellar electrokinetic chromatography. Crystal structure of 2,3,5-trichloropyridine has been reported. Mol­ecules of 2,3,5-trichloropyridine in crystal are stacked along the short a axis and forms a layer structure. 2,3,5-Trichloropyridine is reported to undergo nucleophilic displacement reaction in ionic liquid to afford the corresponding 2-aryloxylpropionate.

Application

2,3,5-Trichloropyridine may be used in the synthesis of 3,5-dichloro-2-arylpyridines via palladium acetate-catalyzed ligand-free Suzuki reaction with arylboronic acids.

Safety Information

• pictograms: GHS06,GHS05
• signalword: Danger
• hcodes: H301,H317,H318,H412
• pcodes: P261 - P273 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Sens. 1
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves