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422886

Sigma-Aldrich

(S)-(+)-2-(Aminomethyl)pyrrolidine

97%

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About This Item

Empirical Formula (Hill Notation):
C5H12N2
CAS Number:
Molecular Weight:
100.16
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22

Pricing and availability is not currently available.

Quality Level

assay

97%

form

liquid

optical activity

[α]20/D +20°, c = 1 in chloroform

refractive index

n20/D 1.482 (lit.)

bp

65 °C/11 mmHg (lit.)

density

0.933 g/mL at 25 °C (lit.)

functional group

amine

SMILES string

NC[C@@H]1CCCN1

InChI

1S/C5H12N2/c6-4-5-2-1-3-7-5/h5,7H,1-4,6H2/t5-/m0/s1

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This Item
MABS1990MSAB1403218SAB1405482
antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

biological source

rabbit

biological source

mouse

biological source

mouse

biological source

mouse

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

100

species reactivity

human

species reactivity

rat, mouse, hamster, porcine, human, chicken, monkey, rabbit

species reactivity

human

species reactivity

human

Gene Information

human ... RHOA(387), RHOB(388)

Gene Information

human ... RHOB(388)

Gene Information

human ... RHOD(29984)

Gene Information

human ... RND3(390)

clone

polyclonal

clone

7F7, monoclonal

clone

1E7, monoclonal

clone

polyclonal

General description

(S)-(+)-2-(Aminomethyl)pyrrolidine is a chiral vicinal diamine.

Application

(S)-(+)-2-(Aminomethyl)pyrrolidine can be used as an organocatalyst:
  • For the asymmetric transformation of (S)-alanine.[1]
  • In the asymmetric α-fluorination of linear and branched aldehydes using N-fluorobenzenesulfonamide as the fluorinating agent.[2]

It can also be used as a reactant to prepare Schiff base metal complexes with pyrrolidine fragment as a ligand in asymmetric synthesis.[3]
Used in the synthesis of compounds with antitumor activity.[4]

pictograms

FlameExclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

116.6 °F - closed cup

flash_point_c

47 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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