423955

Methyl 2-methylglycidate

99%

• Empirical Formula (Hill Notation): C₅H₈O₃
• CAS Number: 58653-97-7
• Molecular Weight: 116.12
• MDL number: MFCD00198125
• UNSPSC Code: 12352100
• PubChem Substance ID: 24866542
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 99%
• refractive index: n20/D 1.418 (lit.)
• bp: 62-65 °C/32 mmHg (lit.)
• density: 1.097 g/mL at 25 °C (lit.)
• functional group: ester; ether
• SMILES string: COC(=O)C1(C)CO1
• InChI: 1S/C5H8O3/c1-5(3-8-5)4(6)7-2/h3H2,1-2H3
• InChI key: OSYXXQUUGMLSGE-UHFFFAOYSA-N

Description

General description

Methyl 2-methylglycidate (methyl 2-methyloxirane-2-carboxylate) is an ester derived epoxide. It is reported to be formed by the reaction of methyl pyruvate with diazomethane. It is formed as an intermediate in the synthesis of 1,2,4-oxadiazole derivatives.

Application

Methyl 2-methylglycidate may be used in the synthesis of:

• 2-methyl-2-hydroxy-1-propanol
• 2,3-dihydroxy-2-methyl propionic acid
• methyl 2-hydroxy-3-((4-methoxyphenyl)sulfonyl)-2-methylpropanoate

Safety Information

• pictograms: GHS02,GHS07
• signalword: Warning
• hcodes: H226,H315,H319,H335
• pcodes: P210 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 129.2 °F - closed cup
• flash_point_c: 54 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter