437948

2-Chloro-1,1,1-trimethoxyethane

97%

• Synonym(s): Trimethyl chloro-orthoacetate
• Linear Formula: ClCH₂C(OCH₃)₃
• CAS Number: 74974-54-2
• Molecular Weight: 154.59
• MDL number: MFCD00216629
• UNSPSC Code: 12352100
• PubChem Substance ID: 24867410
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 97%
• refractive index: n20/D 1.425 (lit.)
• bp: 138 °C (lit.)
• density: 1.147 g/mL at 25 °C (lit.)
• functional group: chloro; ether
• SMILES string: COC(CCl)(OC)OC
• InChI: 1S/C5H11ClO3/c1-7-5(4-6,8-2)9-3/h4H2,1-3H3
• InChI key: NPEIUNVTLXEOLT-UHFFFAOYSA-N

Description

General description

2-Chloro-1,1,1-trimethoxyethane is a chloromethyl heterocyclic compound. It participates in the synthesis of 2-phenyl-1,3,4-oxadiazole derivatives.

Application

2-Chloro-1,1,1-trimethoxyethane may be used for the synthesis of chlorotriazolinone, an NK₁ antagonist and 2-chloromethyl-7-[3-(trifluoromethyl)pyridin-2-yl]-3H-quinazolin-4-one.

Safety Information

• pictograms: GHS02
• signalword: Warning
• hcodes: H226
• Hazard Classifications: Flam. Liq. 3
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 109.4 °F - closed cup
• flash_point_c: 43 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter