469602

4-Benzyloxybutyric acid

95%

• Linear Formula: C₆H₅CH₂O(CH₂)₃CO₂H
• CAS Number: 10385-30-5
• Molecular Weight: 194.23
• MDL number: MFCD01321257
• UNSPSC Code: 12352100
• PubChem Substance ID: 24870473
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 95%
• refractive index: n20/D 1.512 (lit.)
• bp: 135 °C/0.3 mmHg (lit.)
• density: 1.097 g/mL at 25 °C (lit.)
• functional group: carboxylic acid; ether; phenyl
• SMILES string: OC(=O)CCCOCc1ccccc1
• InChI: 1S/C11H14O3/c12-11(13)7-4-8-14-9-10-5-2-1-3-6-10/h1-3,5-6H,4,7-9H2,(H,12,13)
• InChI key: CXEFZVVLTJQWBF-UHFFFAOYSA-N

Description

General description

4-Benzyloxybutyric acid can be synthesized from γ-butyrolactone. It participates in the asymmetric total synthesis of erythromycin.

Application

4-Benzyloxybutyric acid may be used in the synthesis of benzyloxybutyryl (BOB) esters of alcohols by standard acylation techniques or by the Jacobsen asymmetric nucleophilic ring opening of epoxides.

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 235.4 °F - closed cup
• flash_point_c: 113 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter