480118

3,4-Dimethoxyphenylboronic acid

≥95.0%

• Linear Formula: (CH₃O)₂C₆H₃B(OH)₂
• CAS Number: 122775-35-3
• Molecular Weight: 181.98
• MDL number: MFCD01074574
• UNSPSC Code: 12352103
• PubChem Substance ID: 24871548
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: ≥95.0%
• mp: 245-250 °C (lit.)
• SMILES string: COc1ccc(cc1OC)B(O)O
• InChI: 1S/C8H11BO4/c1-12-7-4-3-6(9(10)11)5-8(7)13-2/h3-5,10-11H,1-2H3
• InChI key: RCVDPBFUMYUKPB-UHFFFAOYSA-N

Description

Application

3,4-Dimethoxyphenylboronic acid can be used:

• As a substrate in the cross-coupling reaction with 5,7-dichloropyrido[4,3-d]pyrimidine catalyzed by palladium.
• As a starting material for the synthesis of buflavine 1, a natural alkaloid.
• In one of the key synthetic steps for the preparation of lipidated malarial glycosylphosphatidylinositols (GPI) disaccharide.
• To prepare 3,3″,4,4″-tetramethoxy-1,1′:4′,1″-terphenyl by reacting with 1,4-dibromobenzene using Pd catalyst.

Other Notes

Contains varying amounts of anhydride

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)