483486

2,4-Dimethoxyphenylboronic acid

95%

• Linear Formula: (CH₃O)₂C₆H₃B(OH)₂
• CAS Number: 133730-34-4
• Molecular Weight: 181.98
• MDL number: MFCD01074590
• UNSPSC Code: 12352103
• PubChem Substance ID: 24871896
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: 95%
• mp: 125-127 °C (lit.)
• SMILES string: COc1ccc(B(O)O)c(OC)c1
• InChI: 1S/C8H11BO4/c1-12-6-3-4-7(9(10)11)8(5-6)13-2/h3-5,10-11H,1-2H3
• InChI key: SQTUYFKNCCBFRR-UHFFFAOYSA-N

Description

Application

2,4-Dimethoxyphenylboronic acid can be used:

• As a reactant in meatal-catalyzed Suzuki−Miyaura cross-coupling reaction.
• To prepare hydroxy(trimethoxy)phenanthrene by cross-coupling with bromo(benzyloxy)methoxybenzaldehyde followed by condensation and debenzylation reaction.
• To synthesize 2,4-dimethoxy-1-(trifluoromethyl)benzene via Cu-catalyzed trifluoromethylation reaction.

Other Notes

Contains varying amounts of anhydride

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)