525898

Methyl (1-methylindolyl)-3-glyoxylate

97%

• Empirical Formula (Hill Notation): C₁₂H₁₁NO₃
• CAS Number: 151490-40-3
• Molecular Weight: 217.22
• MDL number: MFCD02683553
• UNSPSC Code: 12352100
• PubChem Substance ID: 24874518
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 97%
• mp: 96-100 °C (lit.)
• SMILES string: COC(=O)C(=O)c1cn(C)c2ccccc12
• InChI: 1S/C12H11NO3/c1-13-7-9(11(14)12(15)16-2)8-5-3-4-6-10(8)13/h3-7H,1-2H3
• InChI key: SBHIWUQNUXJUMN-UHFFFAOYSA-N

Description

General description

Methyl (1-methylindolyl)-3-glyoxylate can be prepared from 1-methylindole.

Application

• Reactant for synthesis of sotrastaurin analogs
• Reactant for preparation of protein kinase C (PKC) inhibitors
• Reactant for preparation of indolyl diols

Methyl (1-methylindolyl)-3-glyoxylate may be used to synthesize 3-[(1-methyl)-3-indolyl]-4-(3-indolyl)-1H-pyrrole-2,5-dione and 3,4-[(1-methyl)-3-indolyl]-1H-pyrrole-2,5-dione.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves