526134

tert-Butyldimethylsilyl glycidyl ether

98%

• Empirical Formula (Hill Notation): C₉H₂₀O₂Si
• CAS Number: 78906-15-7
• Molecular Weight: 188.34
• MDL number: MFCD02683555
• UNSPSC Code: 12352100
• PubChem Substance ID: 24874536
• NACRES: NA.22

Properties

• assay: 98%
• refractive index: n20/D 1.531 (lit.)
• bp: 195-197 °C (lit.)
• density: 0.901 g/mL at 25 °C (lit.)
• functional group: ether
• SMILES string: CC(C)(C)[Si](C)(C)OCC1CO1
• InChI: 1S/C9H20O2Si/c1-9(2,3)12(4,5)11-7-8-6-10-8/h8H,6-7H2,1-5H3
• InChI key: YANSSVVGZPNSKD-UHFFFAOYSA-N

Description

General description

tert-Butyldimethylsilyl glycidyl ether [tert-butyl-dimethyl-(oxiran-2-ylmethoxy)silane] can be synthesized from glycidol, via hydrolytic kinetic resolution (HKR) in the presence of R-(salen)Co complex and water.

Application

tert-Butyldimethylsilyl glycidyl ether may be used to synthesize (R/S)-1-benzylamino-3-(tert-butyldimethylsilyloxy)propan-2-ol and (2R/2S)-1-(tert-butyldimethylsilyloxy)-3-{[(4S)-2,2-dimethyl-1,3-dioxolan-4-ylmethyl]amino}propan-2-ol.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 158.0 °F - closed cup
• flash_point_c: 70 °C - closed cup
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)