528102

6-Chloronicotinoyl chloride

97%

• Empirical Formula (Hill Notation): C₆H₃Cl₂NO
• CAS Number: 66608-11-5
• Molecular Weight: 176.00
• MDL number: MFCD00051775
• UNSPSC Code: 12352100
• PubChem Substance ID: 24874669
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 97%
• mp: 48-51 °C (lit.)
• functional group: acyl chloride; chloro
• SMILES string: ClC(=O)c1ccc(Cl)nc1
• InChI: 1S/C6H3Cl2NO/c7-5-2-1-4(3-9-5)6(8)10/h1-3H
• InChI key: FMEBIWNKYZUWFV-UHFFFAOYSA-N

Description

General description

6-Chloronicotinoyl chloride undergoes esterification reaction with diethylene glycol and pentaethylene glycol.

Application

6-Chloronicotinoyl chloride may be used to synthesize:

• [³H]imidacloprid (a candidate radioligand)
• [³H]acetamiprid
• N,N′-(1,4-phenylene)bis(6-(4-aminophenoxy) nicotinamide)
• 3-acetyl-6-chloropyridine
• 1,3-dipropyl-8(6-chloro-3-pyridyl)xanthine

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 230.0 °F - closed cup
• flash_point_c: 110 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges