55452

D-α-Hydroxyisovaleric acid

≥98.0% (T)

• Synonym(s): (R)-2-Hydroxy-3-methylbutyric acid
• Empirical Formula (Hill Notation): C₅H₁₀O₃
• CAS Number: 17407-56-6
• Molecular Weight: 118.13
• Beilstein/REAXYS Number: 1721139
• MDL number: MFCD00066442
• UNSPSC Code: 51113400
• PubChem Substance ID: 57651528
• NACRES: NA.22

Properties

• assay: ≥98.0% (T)
• form: solid
• optical activity: [α]20/D −17±1°, c = 1% in chloroform
• mp: 64-67 °C
• functional group: carboxylic acid; hydroxyl
• SMILES string: CC(C)[C@@H](O)C(O)=O
• InChI: 1S/C5H10O3/c1-3(2)4(6)5(7)8/h3-4,6H,1-2H3,(H,7,8)/t4-/m1/s1
• InChI key: NGEWQZIDQIYUNV-SCSAIBSYSA-N

Description

Application

D-α-Hydroxyisovaleric acid may be used in the preparation of biodegradable, optically active and isotactic poly(D-2-hydroxy-3-methylbutanoic acid).

Other Notes

This chiral α-hydroxy acid is used for the synthesis of peptides and depsipeptides. It is further used as chiral building block. Synthesis of α-substituted α-hydroxy acids via dioxolanone intermediates.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves