561657

(1,3-Dioxan-2-ylethyl)magnesium bromide solution

0.5 M in THF

• Synonym(s): 1,3-Dioxane - 2-ethyl- magnesium complex, [2-(1,3-Dioxan-2-yl)ethyl]magnesium bromide
• Empirical Formula (Hill Notation): C₆H₁₁BrMgO₂
• CAS Number: 480438-44-6
• Molecular Weight: 219.36
• MDL number: MFCD00061518
• UNSPSC Code: 12352103
• PubChem Substance ID: 24879959
• NACRES: NA.22

Properties

• reaction suitability: reaction type: Grignard Reaction
• Quality Level: 100
• concentration: 0.5 M in THF
• bp: 65 °C
• density: 0.951 g/mL at 25 °C
• functional group: ether
• storage temp.: 2-8°C
• SMILES string: Br[Mg]CCC1OCCCO1
• InChI: 1S/C6H11O2.BrH.Mg/c1-2-6-7-4-3-5-8-6;;/h6H,1-5H2;1H;/q;;+1/p-1
• InChI key: JYNXRXBIEHSSLR-UHFFFAOYSA-M

Description

Application

(1,3-Dioxan-2-ylethyl)magnesium bromide can be used:

• In a Grignard addition-acylation method for the preparation of enamides.
• To prepare trisubstituted allenes by reacting with propargylic ammonium salts.
• In one of the key synthetic steps for the synthesis of febrifugine based antimalarial drugs.

Legal Information

Product of Rieke Metals, Inc.
Rieke is a registered trademark of Rieke Metals, Inc.

Safety Information

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H319,H335,H351
• pcodes: P261 - P281 - P305 + P351 + P338
• Hazard Classifications: Carc. 2 - Eye Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• supp_hazards: EUH019
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: No data available
• flash_point_c: No data available