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645826

Sigma-Aldrich

N-(4-Methoxybenzylidene)-4-methoxyaniline

97%

Synonym(s):

4-Methoxy-N-(4-methoxybenzylidene)aniline, N-(4-Methoxybenzylidene)-4-anisidine

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About This Item

Empirical Formula (Hill Notation):
C15H15NO2
CAS Number:
1749-08-2
Molecular Weight:
241.29
MDL number:
MFCD00025800
UNSPSC Code:
12352100
PubChem Substance ID:
24883402
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

100

assay

97%

form

solid

mp

146-150 °C (lit.)

functional group

imine

SMILES string

COc1ccc(cc1)\C=N\c2ccc(OC)cc2

InChI

1S/C15H15NO2/c1-17-14-7-3-12(4-8-14)11-16-13-5-9-15(18-2)10-6-13/h3-11H,1-2H3/b16-11+

InChI key

ZDOHZYPZEUJYKN-LFIBNONCSA-N

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1 of 4

This Item
EHU015981EMU003391EMU005061
MISSION® esiRNA targeting mouse Cdc42ep2

EMU007361

MISSION® esiRNA

MISSION® esiRNA targeting human CDC42EP2

EHU015981

MISSION® esiRNA

MISSION® esiRNA targeting mouse Arap3

EMU003391

MISSION® esiRNA

MISSION® esiRNA targeting mouse Acly

EMU005061

MISSION® esiRNA

esiRNA cDNA target sequence

CAGCTCTCCAAAGGGACTTGCATCCATCTAGAAGAGAGGAGGGTGTATTCACCACCCTGTCTTTGTTGGCCTTTAATCTAACTTTACCTGACACCTTGGGCCAACTTTGATCACATCTCACCCTCTACTTTTGTTTTGTTTTTGGCAAGAGTGGACATTGGCCCTCTGGAGCCTGTTTTGGGCAGAGGGTGTTGAGAGAGTACTGAGGACTGAGCGGCCAGGACTGTGTGCTGAAGTCACCATGTCCACCAAGGTCCCCATCTATTTGAAACGTGGCAGCCGCAAAGGCAAGAAAGAGAAGCTTCGGGACCTGCTGTCCTCAGACATGATCAGCCCACCACTTGGGGACTTCCGTCACACTATTCACATTGGCAGCGGTGGCGGAGATGACATGTTTGGGGACATCTCCTTC

esiRNA cDNA target sequence

TCAGAAGAGTTTGCCGTCCTTTGGGGAGAACGTGATTTTTGTTATCTCAGCCCACTGACTTCATTGATCTCTAATCTTTTTTAATTCCTTGGGCCAACTTTGTTCGTGCCCCCACACTGTAGCCAGAAGCCCGTTGGCGAGCTCTGGCACCTGCAAACCACCCCGTGGAACGAGTGTTTCCTCTGGCTGAGGGTTGGAGAGGAGGTGTGGTCTCAGCAGGCGGCCCGTAGCCTCACAGCCAGGCCTGGTGGTGAGGTCACCATGTCCACCAAGGTGCCCATCTATCTGAAGCGTGGCAGTCGCAAGGGCAAGAAGGAGAAGCTTCGGGACCTGCTGTCCTCGGACATGATCAGCCCACCGCTGGGGGACTTCCGCCACACCATTCATATTGGCAGTGGCGGCGGCAGTGACATGTTTGGCGACATC

esiRNA cDNA target sequence

GCGCCTGGAGAAGTACAAAGAAGTGATTAGCTGCCTGCCTCGAGTCAACCGCAGAACACTGGCCACCCTCATCGGGCATCTGTACCGGGTGCAGAAGTGTGCGTCTCTAAACCAGATGTGCACGCGGAACCTGGCCCTACTGTTTGCACCTAGTGTGTTCCAGACAGATGGGCGGGGAGAGCATGAGGTTCGGGTACTGCAGGAGCTCATCGATGGCTACATCTCTGTTTTTGATATTGACTCGGACCAGGCAGCTCAGATTGACTTGGAGGTCAGTCTCATTACCACCTGGAAGGATGTGCAGTTGTCCCAGGCTGGAGACCTCATCATGGAGGTTTACATAGAACAGCAGCTCCCGGACAACTGTGTCACCCTAAAGGTATCCCCAACACTGACTGCTGAGGA

esiRNA cDNA target sequence

CATCGGCCATCGAGTAAAATCGATAAACAACCCAGACATGCGAGTGCAGATCCTCAAGGACTTCGTCAAACAGCACTTCCCCGCCACCCCGCTGCTCGACTATGCCCTGGAAGTGGAGAAGATTACCACCTCCAAGAAGCCAAATCTTATCCTGAATGTGGACGGCTTCATCGGCGTTGCGTTTGTGGACATGCTCAGGAACTGTGGCTCCTTCACCCGGGAGGAAGCTGATGAATATGTTGACATTGGAGCCCTCAATGGCATCTTTGTGCTAGGAAGGAGTATGGGCTTCATTGGGCACTACCTTGACCAGAAGAGGCTGAAGCAAGGGCTGTATCGTCACCCCTGGGATGACATTTCCTATGTTCTTCCAGAACACATGAGCATGTAACTGAGCCAGGAGCCCTA

Gene Information

mouse ... CDC42EP2(104252), Cdc42ep2(104252)

Gene Information

human ... CDC42EP2(10435), CDC42EP2(10435)

Gene Information

mouse ... ARAP3(106952), Arap3(106952)

Gene Information

mouse ... ACLY(104112), Acly(104112)

Ensembl | mouse accession no.

ENSMUSG00000045664

Ensembl | mouse accession no.

-

Ensembl | mouse accession no.

ENSMUSG00000024451

Ensembl | mouse accession no.

ENSMUSG00000020917

product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

NCBI accession no.

NM_026772

NCBI accession no.

NM_006779

NCBI accession no.

NM_139206

NCBI accession no.

NM_134037

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
06508MC
09017KC

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Rong Chen et al.
Biochemistry, 57(18), 2704-2710 (2018-04-14)
Molecular dynamics simulations are employed to determine the inhibitory mechanisms of three drugs, 5-(4-phenoxybutoxy)psoralen (PAP-1), vernakalant, and flecainide, on the voltage-gated K+ channel Kv1.5, a target for the treatment of cardiac arrhythmia. At neutral pH, PAP-1 is neutral, whereas the
Jonas Goldin Diness et al.
Circulation. Arrhythmia and electrophysiology, 10(10) (2017-10-12)
Evidence has emerged that small-conductance Ca2+-activated K+ (SK) channels constitute a new target for treatment of atrial fibrillation (AF). SK channels are predominantly expressed in the atria as compared with the ventricles. Various marketed antiarrhythmic drugs are limited by ventricular
Gerrit Frommeyer et al.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 19(5), 866-873 (2016-10-06)
The antiarrhythmic drug vernakalant exerts antiarrhythmic effects in atrial fibrillation. Recent experimental data suggest interactions with the late sodium current and antiarrhythmic effects in ventricular arrhythmias. We aimed at investigating whether treatment with vernakalant reduces polymorphic ventricular tachycardia (VT) in
Toshiki Chiba et al.
Journal of pharmacological sciences, 130(3), 170-176 (2016-04-02)
Electrical remodeling plays a pivotal role in maintaining the reentry during atrial fibrillation. In this study, we assessed influence of electrical remodeling on pharmacological manipulation of the atrial refractoriness in rabbits. We used an atrial electrical remodeling model of the
Gerrit Frommeyer et al.
Journal of cardiovascular medicine (Hagerstown, Md.), 18(9), 663-668 (2017-07-12)
Current guidelines recommend vernakalant for pharmacologic cardioversion of recent-onset atrial fibrillation. However, this drug is not established as chronic therapy. In total, 15 rabbit hearts were Langendorff-perfused. A burst pacing protocol-induced atrial fibrillation in 7 of 15 hearts at baseline

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