679097

(R)-(−)-2-Methylpyrrolidine

• Empirical Formula (Hill Notation): C₅H₁₁N
• CAS Number: 41720-98-3
• Molecular Weight: 85.15
• MDL number: MFCD07783026
• UNSPSC Code: 12352005
• PubChem Substance ID: 24885467
• NACRES: NA.22

Properties

• refractive index: n20/D 1.4353
• Quality Level: 100
• density: 0.842 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: C[C@@H]1CCCN1
• InChI: 1S/C5H11N/c1-5-3-2-4-6-5/h5-6H,2-4H2,1H3/t5-/m1/s1
• InChI key: RGHPCLZJAFCTIK-RXMQYKEDSA-N

Description

Application

(R)-(−)-2-Methylpyrrolidine, an optically active amine that can be used as a key building block to synthesize:

• 4,5-fused pyridazinone derivatives are applicable as potent histamine H3 receptor antagonists.
• Naphthalenoid histamine H3 receptor antagonist.
• Pyrrolo[2,3-d]pyrimidine derivatives as potent inhibitors of leucine-rich repeat kinase 2.

Safety Information

• pictograms: GHS02,GHS05,GHS07
• signalword: Danger
• hcodes: H225,H302,H314
• pcodes: P210 - P233 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Flam. Liq. 2 - Skin Corr. 1B
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 45.0 °F - closed cup
• flash_point_c: 7.22 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter