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702455

Sigma-Aldrich

1H-Indazole-5-carboxylic acid

97%

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About This Item

Empirical Formula (Hill Notation):
C8H6N2O2
CAS Number:
61700-61-6
Molecular Weight:
162.15
MDL number:
MFCD06804570
UNSPSC Code:
12352100
PubChem Substance ID:
329762377
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

100

assay

97%

form

powder

mp

318-322 °C

functional group

carboxylic acid

SMILES string

OC(=O)c1ccc2[nH]ncc2c1

InChI

1S/C8H6N2O2/c11-8(12)5-1-2-7-6(3-5)4-9-10-7/h1-4H,(H,9,10)(H,11,12)

InChI key

MAVGBUDLHOOROM-UHFFFAOYSA-N

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IGF-Binding Protein-3 human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

SRP3067

IGF-Binding Protein-3 human

Insulin-Like Growth Factor Binding Protein-3 human recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture, ≥95% (SDS-PAGE)

I5278

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IGF-Binding Protein-5 human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

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IGF-Binding Protein-5 human

IGF-Binding Protein 1 human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

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technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

biological source

human

biological source

human

biological source

human

biological source

human

assay

≥98% (HPLC), ≥98% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

assay

≥98% (HPLC), ≥98% (SDS-PAGE)

assay

≥98% (HPLC), ≥98% (SDS-PAGE)

recombinant

expressed in E. coli

recombinant

expressed in NSO cells

recombinant

expressed in E. coli

recombinant

expressed in E. coli

form

lyophilized

form

lyophilized powder

form

lyophilized

form

lyophilized

mol wt

28.8 kDa

mol wt

29 kDa

mol wt

28.6 kDa

mol wt

25.4 kDa

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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    Lot/Batch Number
    MKCG9067
    MKCB7416
    MKBQ5065V
    MKBG8884V
    MKBB6295

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    Patrick Grailhe et al.
    FEBS open bio, 10(10), 2010-2020 (2020-08-19)
    Sphingosine-1 phosphate receptor-1 (S1P1 ) activation maintains endothelial barrier integrity, whereas S1P1 desensitization induces peripheral blood lymphopenia. The latter is exploited in the approval and/or late-stage development of receptor-desensitizing agents targeting the S1P1 receptor in multiple sclerosis, such as siponimod
    Nikolay T Tzvetkov et al.
    European journal of medicinal chemistry, 127, 470-492 (2017-01-21)
    The pharmacological and physicochemical analysis of structurally optimized N-alkyl-substituted indazole-5-carboxamides, developed as potential drug and radioligand candidates for the treatment and diagnosis of Parkinson's disease (PD) and other neurological disorders, is reported. Recent efforts have been focused on the development

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