79421

Phosphazene base P₄-t-Bu solution

~0.8 M in hexane

• Synonym(s): 1-tert-Butyl-4,4,4-tris(dimethylamino)-2,2-bis[tris(dimethylamino)-phosphoranylidenamino]-2λ⁵,4λ⁵-catenadi(phosphazene)
• Empirical Formula (Hill Notation): C₂₂H₆₃N₁₃P₄
• CAS Number: 111324-04-0
• Molecular Weight: 633.72
• Beilstein/REAXYS Number: 5784423
• MDL number: MFCD00145114
• UNSPSC Code: 12352001
• PubChem Substance ID: 57652794
• NACRES: NA.22

Properties

• form: liquid
• concentration: ~0.8 M in hexane
• density: 0.850-0.875 g/mL at 20 °C
• functional group: amine
• SMILES string: CN(C)P(=NP(=NC(C)(C)C)(N=P(N(C)C)(N(C)C)N(C)C)N=P(N(C)C)(N(C)C)N(C)C)(N(C)C)N(C)C
• InChI: 1S/C22H63N13P4/c1-22(2,3)23-36(24-37(27(4)5,28(6)7)29(8)9,25-38(30(10)11,31(12)13)32(14)15)26-39(33(16)17,34(18)19)35(20)21/h1-21H3
• InChI key: NSRBCQCXZAYQHF-UHFFFAOYSA-N

Description

Application

Phosphazene Bases: a Family of Extremely Strong, Non-Ionic, Non-Charged Nitrogen–Bases

Caution

Product crystallizes out of solution, can be redissolved on heating to 40°C.

Other Notes

Extremely strong, hindered, neutral nitrogen base; it is about 1018 times more basic than DBU [pKa (DMSO) 30.25]. Stable to hydrolysis and unaffected by alkylating agents; Base for enolate formation and stereoselective alkylation.

Safety Information

• pictograms: GHS02,GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H225,H304,H314,H336,H361f,H372,H412
• pcodes: P210 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Aquatic Chronic 3 - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 2 - Skin Corr. 1B - STOT RE 1 Inhalation - STOT SE 3
• target_organs: Central nervous system, Nervous system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: -14.8 °F - closed cup
• flash_point_c: -26 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter