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915033

Sigma-Aldrich

TissueFab® bioink Bone

Vis/405 nm

Synonym(s):

3D Bioprinting, Bioink, GelMA, TissueFab

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About This Item

UNSPSC Code:
12352201
NACRES:
NA.23
Pricing and availability is not currently available.

description

0.2 μm sterile filtered
suitable for 3D bioprinting applications

Quality Level

100

form

gel form (viscous)

impurities

≤5 CFU/g Bioburden (Fungal)
≤5 CFU/g Bioburden (Total Aerobic)

color

white

pH

6.5-7.5

application(s)

3D bioprinting

storage temp.

2-8°C

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1 of 4

This Item
Z112178Z112135Z112151
32mm Round cell window KBr, Undrilled

Z112119

32mm Round cell window

32mm Round cell window KBr, Drilled

Z112178

32mm Round cell window

32mm Round cell window BaF2, Undrilled

Z112135

32mm Round cell window

32mm Round cell window NaCl, Drilled

Z112151

32mm Round cell window

material

KBr

material

KBr

material

BaF2

material

NaCl

packaging

pkg of (contains 1 window)

packaging

pkg of (contains 1 window)

packaging

pkg of (contains 1 window)

packaging

pkg of (contains 1 window)

technique(s)

IR spectroscopy: suitable

technique(s)

IR spectroscopy: suitable

technique(s)

IR spectroscopy: suitable

technique(s)

IR spectroscopy: suitable

diam. × thickness

32 mm × 3 mm

diam. × thickness

32 mm × 3 mm

diam. × thickness

32 mm × 3 mm

diam. × thickness

32 mm × 3 mm

Application

TissueFab® - GelMA-Bone-Vis bioink is designed for promoting osteogenic differentiation of stem cells. It is based on Gelatin methacryloyl (GelMA) - Hydroxyapatite (HAp) hydrogel system. HAp is a highly crystalline form of calcium phosphate. HAp has a chemical similarity with the mineralized phase of bone which accounts for their excellent biocompatibility and osteoinductive and osteoconductive properties favorable for bone regeneration. HAp-containing hydrogels has been studied in literature to demonstrate their processability with different additive manufacturing approaches. Printing of cell laden structures with HAp containing bioink formulations have shown superior osteogenic properties.

Packaging

Product contains 10 ml of solution packaged in glass bottle.

Legal Information

TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Soonsang Yoon et al.
Journal of neuromuscular diseases, 5(1), 59-73 (2017-12-28)
Mutations in the LAMA2 gene encoding laminin-α2 cause congenital muscular dystrophy Type 1A (MDC1A), a severe recessive disease with no effective treatment. Previous studies have shown that aberrant activation of caspases and cell death through a pathway regulated by BAX
Jessica X Chong et al.
American journal of human genetics, 96(5), 841-849 (2015-05-11)
Multiple pterygium syndrome (MPS) is a phenotypically and genetically heterogeneous group of rare Mendelian conditions characterized by multiple pterygia, scoliosis, and congenital contractures of the limbs. MPS typically segregates as an autosomal-recessive disorder, but rare instances of autosomal-dominant transmission have
Catrin Sian Rutland et al.
Development (Cambridge, England), 138(18), 3955-3966 (2011-08-25)
The expression and function of embryonic myosin heavy chain (eMYH) has not been investigated within the early developing heart. This is despite the knowledge that other structural proteins, such as alpha and beta myosin heavy chains and cardiac alpha actin
Reha M Toydemir et al.
Nature genetics, 38(5), 561-565 (2006-04-28)
The genetic basis of most conditions characterized by congenital contractures is largely unknown. Here we show that mutations in the embryonic myosin heavy chain (MYH3) gene cause Freeman-Sheldon syndrome (FSS), one of the most severe multiple congenital contracture (that is
Sachiko Homma et al.
Skeletal muscle, 6(1), 42-42 (2016-12-03)
Nuclear bodies, such as nucleoli, PML bodies, and SC35 speckles, are dynamic sub-nuclear structures that regulate multiple genetic and epigenetic processes. Additional regulation is provided by RNA/DNA handling proteins, notably TDP-43 and FUS, which have been linked to ALS pathology.

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