923931
Pomalidomide-4-piperidine-C1-piperazine hydrochloride
Synonym(s):
2-(2,6-Dioxopiperidin-3-yl)-4-(4-(piperazin-1-ylmethyl)piperidin-1-yl)isoindoline-1,3-dione hydrochloride, Crosslinker−E3 ligase ligand conjugate, Protein degrader building block
About This Item
Recommended Products
ligand
pomalidomide
Quality Level
reaction suitability
reactivity: carboxyl reactive
reagent type: ligand-linker conjugate
functional group
amine
storage temp.
2-8°C
SMILES string
O=C1C(N2C(C(C=CC=C3N(CC4)CCC4CN5CCNCC5)=C3C2=O)=O)CCC(N1)=O.Cl
InChI
1S/C23H29N5O4.ClH/c29-19-5-4-18(21(30)25-19)28-22(31)16-2-1-3-17(20(16)23(28)32)27-10-6-15(7-11-27)14-26-12-8-24-9-13-26;/h1-3,15,18,24H,4-14H2,(H,25,29,30);1H
InChI key
HICUONDYEDHQSV-UHFFFAOYSA-N
Related Categories
1 of 4
This Item | 923877 | 923885 | 923958 |
---|---|---|---|
Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
reaction suitability reactivity: carboxyl reactive, reagent type: ligand-linker conjugate | reaction suitability reactivity: carboxyl reactive, reagent type: ligand-linker conjugate | reaction suitability reactivity: carboxyl reactive, reagent type: ligand-linker conjugate | reaction suitability reactivity: carboxyl reactive, reagent type: ligand-linker conjugate |
storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
ligand pomalidomide | ligand pomalidomide | ligand pomalidomide | ligand 6F,C5-Pomalidomide |
functional group amine | functional group amine | functional group amine | functional group amine |
Application
Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
Protein Degrader Building Blocks
Other Notes
Legal Information
signalword
Danger
hcodes
Hazard Classifications
Repr. 1B
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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