B56501

4-Bromoanisole

≥99.0%

• Synonym(s): 1-Bromo-4-methoxybenzene
• Linear Formula: BrC₆H₄OCH₃
• CAS Number: 104-92-7
• Molecular Weight: 187.03
• Beilstein/REAXYS Number: 1237590
• EC Number: 203-252-1
• MDL number: MFCD00000097
• UNSPSC Code: 12352100
• PubChem Substance ID: 24891850
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: ≥99.0%
• form: liquid
• refractive index: n20/D 1.564 (lit.)
• bp: 223 °C (lit.)
• mp: 9-10 °C (lit.)
• density: 1.494 g/mL at 25 °C (lit.)
• SMILES string: COc1ccc(Br)cc1
• InChI: 1S/C7H7BrO/c1-9-7-4-2-6(8)3-5-7/h2-5H,1H3
• InChI key: QJPJQTDYNZXKQF-UHFFFAOYSA-N

Description

General description

4-Bromoanisole is a useful brominating reagent. It is formed as reaction product in the reaction between HOBr and anisole. Suzuki coupling of 4-bromoanisole with phenylboronic acid catalyzed by palladium pincer complexes has been studied. Heck Reaction of 4-bromoanisole with ethyl acrylates in room-temperature ionic liquids is reported to afford ethyl 4-methoxycinnamate.

Application

4-Bromoanisole was used in the synthesis of aryl 1,3-diketones.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315
• pcodes: P264 - P270 - P280 - P301 + P312 - P302 + P352 - P332 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Skin Irrit. 2
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 2
• flash_point_f: 201.2 °F
• flash_point_c: 94 °C
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)