C80407

Cinchonidine

96%

• Synonym(s): (−)-Cinchonidine
• Empirical Formula (Hill Notation): C₁₉H₂₂N₂O
• CAS Number: 485-71-2
• Molecular Weight: 294.39
• Beilstein/REAXYS Number: 89690
• EC Number: 207-622-3
• MDL number: MFCD00006783
• UNSPSC Code: 12352005
• PubChem Substance ID: 24893015
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: 96%
• form: powder
• optical activity: [α]23/D −109.2°, c = 1.5 in ethanol
• mp: 204-206 °C (lit.)
• SMILES string: O[C@@H]([C@@H]1C[C@@H]2CCN1C[C@@H]2C=C)c3ccnc4ccccc34
• InChI: 1S/C19H22N2O/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17/h2-7,9,13-14,18-19,22H,1,8,10-12H2/t13-,14-,18-,19+/m0/s1
• InChI key: KMPWYEUPVWOPIM-KODHJQJWSA-N
• Gene Information: human ... CYP2D6(1565)

Description

General description

Cinchonidine is a cinchona alkaloid, which belongs to the orthorhombic crystal system and P212121 space group.

Application

The enantioselective hydrogenation of ethyl pyruvate in the presence of cinchonidine modified platinum/alumina catalyst leads to the enantiomeric excess of ethyl (R)-lactate.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H317,H319
• pcodes: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1A
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type N95 (US)