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CDS001470

Sigma-Aldrich

2,4,5-Trimethyl-2,5-dihydro-1,3-oxazole

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About This Item

Empirical Formula (Hill Notation):
C6H11NO
Molecular Weight:
113.16
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

Pricing and availability is not currently available.

form

liquid

SMILES string

CC1OC(C)C(C)=N1

InChI

1S/C6H11NO/c1-4-5(2)8-6(3)7-4/h5-6H,1-3H3

InChI key

YFSGRMONVCFYTC-UHFFFAOYSA-N

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This Item
U9132U5382P3988
recombinant

expressed in E. coli (histidine-tagged)

recombinant

expressed in E. coli

recombinant

expressed in E. coli (N-terminal FLAG® tagged)

recombinant

-

assay

≥95% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

technique(s)

ligand binding assay: suitable

technique(s)

-

technique(s)

mass spectrometry (MS): suitable

technique(s)

-

biological source

human

biological source

-

biological source

human

biological source

rabbit

form

buffered aqueous glycerol solution

form

liquid

form

lyophilized powder

form

solution

mol wt

~20 kDa

mol wt

18 kDa

mol wt

10 kDa

mol wt

700 kDa

Other Notes

Please note that Sigma-Aldrich provides this product to early discovery researchers as part of a collection of unique chemicals. Sigma-Aldrich does not collect analytical data for this product. Buyer assumes responsibility to confirm product identity and/or purity. All sales are final.

NOTWITHSTANDING ANY CONTRARY PROVISION CONTAINED IN SIGMA-ALDRICH′S STANDARD TERMS AND CONDITIONS OF SALE OR AN AGREEMENT BETWEEN SIGMA-ALDRICH AND BUYER, SIGMA-ALDRICH SELLS THIS PRODUCT "AS-IS" AND MAKES NO REPRESENTATION OR WARRANTY WHATSOEVER WITH RESPECT TO THIS PRODUCT, INCLUDING ANY (A) WARRANTY OF MERCHANTABILITY; (B) WARRANTY OF FITNESS FOR A PARTICULAR PURPOSE; OR (C) WARRANTY AGAINST INFRINGEMENT OF INTELLECTUAL PROPERTY RIGHTS OF A THIRD PARTY; WHETHER ARISING BY LAW, COURSE OF DEALING, COURSE OF PERFORMANCE, USAGE OF TRADE OR OTHERWISE.

hcodes

Hazard Classifications

Aquatic Chronic 3

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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    The Journal of biological chemistry, 288(44), 32050-32063 (2013-09-21)
    Recent studies link synaptojanin 1 (synj1), the main phosphoinositol (4,5)-biphosphate phosphatase (PI(4,5)P2-degrading enzyme) in the brain and synapses, to Alzheimer disease. Here we report a novel mechanism by which synj1 reversely regulates cellular clearance of amyloid-β (Aβ). Genetic down-regulation of
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