Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

H11904

Sigma-Aldrich

2,5-Hexanediol

99% (mixture of isomers)

Synonym(s):

2,5-Hexylene glycol

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
CH3CH(OH)CH2CH2CH(OH)CH3
CAS Number:
2935-44-6
Molecular Weight:
118.17
Beilstein/REAXYS Number:
1719248
EC Number:
220-910-3
MDL number:
MFCD00004557
UNSPSC Code:
12352100
PubChem Substance ID:
24895436
NACRES:
NA.22

Quality Level

100

assay

99% (mixture of isomers)

form

liquid

refractive index

n20/D 1.447 (lit.)

bp

216-218 °C (lit.)

density

0.961 g/mL at 25 °C (lit.)

SMILES string

CC(O)CCC(C)O

InChI

1S/C6H14O2/c1-5(7)3-4-6(2)8/h5-8H,3-4H2,1-2H3

InChI key

OHMBHFSEKCCCBW-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

2,5-Hexanediol can be used as:
  • A reactant to synthesize N-substituted pyrroles by oxidative coupling with primary amines.
  • An alkylating agent to synthesize substituted carbazoles via Friedel-Crafts alkylation with indoles.
  • A monomer in the preparation of polyesters by reacting with diacid chlorides.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

213.8 °F - closed cup

flash_point_c

101 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCP5136
MKCH9878
MKCC6649
MKBW8060V
MKBP8763V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

J Haberland et al.
Applied microbiology and biotechnology, 58(5), 595-599 (2002-04-17)
Diastereoselective reduction of diketones with Lactobacillus kefir DSM 20587 was examined. The reduction of both oxo-functions proceeded highly diastereoselectively. (2 R,5 R)-Hexanediol 3 was produced starting from (2,5)-hexanedione 1 in quantitative yields with enantiomeric excess >99% and diastereomeric excess >99%.
K Kannan et al.
Environmental research, 36(1), 14-25 (1985-02-01)
A preliminary study on immunotoxicologic evaluation of 2,5-hexanediol (one of the principal metabolites of n-hexane), involving multiple immunological parameters, was carried out in mice. Mice were exposed to 2,5-hexanediol at a 1/5 LD50 dose level for 7 days. Pathotoxicological changes
B Bäckström et al.
Archives of toxicology, 67(4), 277-283 (1993-01-01)
Male albino (Sprague Dawley) and pigmented (Norwegian Brown) rats received 1% 2,5-hexanediol (H) in their drinking water for 5 or 8 weeks, respectively. The rats were housed either in 12 h light (average 30 cd/cm2 inside cage) and 12 h
A Bhatt et al.
Journal of applied toxicology : JAT, 8(1), 53-57 (1988-02-01)
The effects of neurotoxic solvents, i.e. 2,5-hexanedione (2,5-HD), 2,5-hexanediol (2,5-HDiol) and the non-neurotoxic solvent, 2,4-hexanedione (2,4-HD) (500 mg/kg body wt./day, i.p.), have been studied on the lipid composition of brain and sciatic nerves in weanling rats. Five-day-old rats were administered
H B Jones et al.
Acta neuropathologica, 58(4), 286-290 (1982-01-01)
Rats were given 2,5-hexanediol, a metabolite of n-hexane, in the drinking water until they developed a marked degree of paresis over about 7 weeks and were then allowed to recover naturally. The time course and the manner of removal of
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service