M14935

5-Methoxy-3-indoleacetic acid

98%

• Synonym(s): 2-(5-Methoxy-3-indolyl)acetic acid
• Empirical Formula (Hill Notation): C₁₁H₁₁NO₃
• CAS Number: 3471-31-6
• Molecular Weight: 205.21
• Beilstein/REAXYS Number: 187161
• EC Number: 222-438-3
• MDL number: MFCD00005638
• UNSPSC Code: 12352100
• PubChem Substance ID: 24896651
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 98%
• mp: 145-148 °C (dec.) (lit.)
• SMILES string: COc1ccc2[nH]cc(CC(O)=O)c2c1
• InChI: 1S/C11H11NO3/c1-15-8-2-3-10-9(5-8)7(6-12-10)4-11(13)14/h2-3,5-6,12H,4H2,1H3,(H,13,14)
• InChI key: COCNDHOPIHDTHK-UHFFFAOYSA-N

Description

Application

• Reactant for preparation of aryloxybenzothiazoles as inhibitors of NO production
• Reactant for preparation of transcription inhibitors of novel Gli1 as antitumor agents
• Reactant for preparation of indole derivatives as NR2B/NMDA receptor antagonists
• Reactant for preparation of indolyl esters and amides related to indomethacin as selective COX-2 inhibitors
• Reactant for preparation of quinoline salicylic acid series of P-selectin antagonists
• Reactant for preparation of prostaglandin D2 receptor antagonists

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)