N17602

5-Nitroindole

98%

• Synonym(s): NSC 520594
• Empirical Formula (Hill Notation): C₈H₆N₂O₂
• CAS Number: 6146-52-7
• Molecular Weight: 162.15
• Beilstein/REAXYS Number: 383777
• EC Number: 228-153-0
• MDL number: MFCD00005673
• UNSPSC Code: 12352100
• PubChem Substance ID: 24897523
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 98%
• form: powder
• mp: 140-142 °C (lit.)
• SMILES string: [O-][N+](=O)c1ccc2[nH]ccc2c1
• InChI: 1S/C8H6N2O2/c11-10(12)7-1-2-8-6(5-7)3-4-9-8/h1-5,9H
• InChI key: OZFPSOBLQZPIAV-UHFFFAOYSA-N

Description

Application

Reactant for preparation of:

• Pharmaceutically active 2-oxo-1-pyrrolidine analogues
• Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
• Protein Kinase Inhibitors and antiproliferative agents
• Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 (mGlu4)
• Antifungal agents
• Cannabinoid receptor type 1 (CB1) antagonists
• Potential anticancer agents
• Potential antivascular agents
• Selective Anti-leukemic agents
• Anti human immunodeficiency virus subtype 1 (HIV-1) agents

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H318
• pcodes: P280 - P301 + P312 + P330 - P305 + P351 + P338 + P310
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves