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QBD10260

Sigma-Aldrich

m-dPEG®8-NHS ester

Synonym(s):

2,5,8,11,14,17,20,23-Octaoxahexacosan-26-oic acid succinimidyl ester, 2,5-Dioxo-1-pyrrolidinyl 4,7,10,13,16,19,22,25-octaoxahexacosanoate, Polyethylene glycol

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About This Item

Empirical Formula (Hill Notation):
C22H39NO12
CAS Number:
756525-90-3
Molecular Weight:
509.54
MDL number:
MFCD13184969
UNSPSC Code:
12352108
PubChem Substance ID:
329823901
NACRES:
NA.22
Pricing and availability is not currently available.

assay

>90%

form

solid or viscous liquid

reaction suitability

reagent type: chemical modification reagent
reagent type: cross-linking reagent
reactivity: amine reactive

polymer architecture

shape: linear
functionality: monofunctional

shipped in

ambient

storage temp.

−20°C

SMILES string

O=C(CCOCCOCCOCCOCCOCCOCCOCCOC)ON1C(CCC1=O)=O

InChI

1S/C22H39NO12/c1-27-6-7-29-10-11-31-14-15-33-18-19-34-17-16-32-13-12-30-9-8-28-5-4-22(26)35-23-20(24)2-3-21(23)25/h2-19H2,1H3

InChI key

IBZNTYBFTKFSMU-UHFFFAOYSA-N

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assay

≥98% (HPLC)

assay

≥98% (TLC and HPLC)

assay

≥97% (HPLC)

assay

≥97% (HPLC)

form

liquid

form

solid

form

liquid

form

liquid

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage condition

OK to freeze, protect from light, desiccated (hygroscopic)

storage condition

OK to freeze, protect from light

storage condition

OK to freeze, desiccated (hygroscopic), protect from light

storage condition

OK to freeze, desiccated (hygroscopic), protect from light

Features and Benefits

The m-dPEG®8-NHS ester provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG®8-NHS ester reacts with amines.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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