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QBD10304

Sigma-Aldrich

m-dPEG®24-NHS ester

Synonym(s):

Polyethylene glycol

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About This Item

Empirical Formula (Hill Notation):
C54H103NO28
Molecular Weight:
1214.39
MDL number:
MFCD11041155
UNSPSC Code:
12352108
PubChem Substance ID:
329823911
NACRES:
NA.22
Pricing and availability is not currently available.

assay

>90%

form

solid or viscous liquid

reaction suitability

reagent type: chemical modification reagent
reagent type: cross-linking reagent
reactivity: amine reactive

polymer architecture

shape: linear
functionality: monofunctional

shipped in

ambient

storage temp.

−20°C

SMILES string

O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC

InChI

1S/C54H103NO28/c1-59-6-7-61-10-11-63-14-15-65-18-19-67-22-23-69-26-27-71-30-31-73-34-35-75-38-39-77-42-43-79-46-47-81-50-51-82-49-48-80-45-44-78-41-40-76-37-36-74-33-32-72-29-28-70-25-24-68-21-20-66-17-16-64-13-12-62-9-8-60-5-4-54(58)83-55-52(56)2-3-53(55

InChI key

VACCUKVGLYJBJU-UHFFFAOYSA-N

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grade

certified reference material, pharmaceutical secondary standard

grade

-

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, pharmaceutical secondary standard

application(s)

pharmaceutical small molecule

application(s)

-

application(s)

pharmaceutical

application(s)

pharmaceutical

agency

traceable to USP 1225419

agency

-

agency

traceable to USP 1225441

agency

traceable to USP 1225420

packaging

pkg of 500 mg

packaging

-

packaging

pkg of 50 mg

packaging

pkg of 1 mL

storage temp.

2-8°C

storage temp.

-

storage temp.

2-30°C

storage temp.

2-8°C

Quality Level

300

Quality Level

200

Quality Level

300

Quality Level

300

Features and Benefits

The m-dPEG®24-NHS ester series of products provide a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG® molecules are hydrophilic and non-immunogenic of exact length. The number after the dPEG® is the specific number of repeat units in the linear chain. Modification with m-dPEG® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG®24-NHS (N-hydroxysuccinimide) ester reacts with amines.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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