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W248800

Sigma-Aldrich

Fumaric acid

FCC, FG

Synonym(s):

Boletic acid, Lichenic acid, Trans-1,2-ethylenedicarboxylic acid

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About This Item

Linear Formula:
HOOCCH=CHCOOH
CAS Number:
110-17-8
Molecular Weight:
116.07
FEMA Number:
2488
Beilstein/REAXYS Number:
605763
EC Number:
203-743-0
Council of Europe no.:
25
MDL number:
MFCD00002700
UNSPSC Code:
12164502
PubChem Substance ID:
24900967
Flavis number:
8.025
NACRES:
NA.21
organoleptic:
odorless
grade:
FG
Halal
Kosher
biological source:
synthetic
food allergen:
no known allergens
Pricing and availability is not currently available.

biological source

synthetic

Quality Level

400

grade

FG
Halal
Kosher

reg. compliance

EU Regulation 1334/2008 & 178/2002
FCC
FDA 21 CFR 117
FDA 21 CFR 172.350
FDA 21 CFR 175.105

vapor pressure

1.7 mmHg ( 165 °C)

form

powder or crystals

autoignition temp.

1364 °F

expl. lim.

40 %

mp

298-300 °C (subl.) (lit.)

application(s)

flavors and fragrances

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577338-U577161-U577339-U
Ascentis® Express 90 Å AQ-C18, 2.7 μm HPLC Guard Cartridge pack of 3 ea, cartridge L × I.D. 0.5 cm × 4.6 mm

577340-U

Ascentis® Express 90 Å AQ-C18, 2.7 μm HPLC Guard Cartridge

Ascentis® Express 90 Å AQ-C18, 2.7 μm HPLC Guard Cartridge pack of 3 ea, cartridge L × I.D. 0.5 cm × 2.1 mm

577338-U

Ascentis® Express 90 Å AQ-C18, 2.7 μm HPLC Guard Cartridge

Ascentis® Express 90 Å AQ-C18, 2.0 μm HPLC Guard Cartridge pack of 3 ea, cartridge L × I.D. 0.5 cm × 2.1 mm

577161-U

Ascentis® Express 90 Å AQ-C18, 2.0 μm HPLC Guard Cartridge

Ascentis® Express 90 Å AQ-C18, 2.7 μm HPLC Guard Cartridge pack of 3 ea, cartridge L × I.D. 0.5 cm × 3 mm

577339-U

Ascentis® Express 90 Å AQ-C18, 2.7 μm HPLC Guard Cartridge

matrix active group

AQ-C18, polar modified bonding phase

matrix active group

AQ-C18, polar modified bonding phase

matrix active group

AQ-C18, polar modified bonding phase

matrix active group

AQ-C18, polar modified bonding phase

particle size

2.7 μm

particle size

2.7 μm

particle size

2 μm

particle size

2.7 μm

agency

suitable for USP L1

agency

suitable for USP L1

agency

suitable for USP L1

agency

suitable for USP L1

technique(s)

HPLC: suitable, LC/MS: suitable

technique(s)

HPLC: suitable, LC/MS: suitable, UHPLC-MS: suitable, UHPLC: suitable

technique(s)

HPLC: suitable, LC/MS: suitable, UHPLC-MS: suitable, UHPLC: suitable

technique(s)

HPLC: suitable, LC/MS: suitable

pore size

90 Å pore size

pore size

90 Å pore size

pore size

90 Å pore size

pore size

90 Å pore size

Application

Fumaric acid is commonly used as a flavoring agent in food industries because of its sour, or acidic flavor.[1] It has low water solubility. In order to increase its application in various foods, fumaric acid is used along with dioctyl sodium sulfosuccinate, a wetting agent.[1][2]

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

523.4 °F

flash_point_c

273 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SHBN5803
SHBL7285
SHBL2384
MKCF8961
MKCD9521

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Bas J Meussen et al.
Applied microbiology and biotechnology, 94(4), 875-886 (2012-04-25)
Rhizopus oryzae is a filamentous fungus belonging to the Zygomycetes. It is among others known for its ability to produce the sustainable platform chemicals L: -(+)-lactic acid, fumaric acid, and ethanol. During glycolysis, all fermentable carbon sources are metabolized to
Tahar Ghnaya et al.
Chemosphere, 90(4), 1449-1454 (2012-10-03)
The implication of organic acids in Pb translocation was studied in two species varying in shoot lead accumulation, Sesuvium portulacastrum and Brassica juncea. Citric, fumaric, malic and α-cetoglutaric acids were separated and determined by HPLC technique in shoots, roots and
Emine Akar et al.
Carbohydrate polymers, 90(4), 1634-1641 (2012-09-05)
A novel biodegradable sodium carboxymethyl cellulose (NaCMC)-based hydrogel was synthesized by using fumaric acid (FA) as a crosslinking agent at various ratios. Hydrogels (CMCF) were characterized using Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), differential scanning calorimetry (DSC), X-ray
Timothy E L Douglas et al.
Macromolecular bioscience, 12(8), 1077-1089 (2012-06-01)
Alkaline phosphatase (ALP), an enzyme involved in mineralization of bone, is incorporated into three hydrogel biomaterials to induce their mineralization with calcium phosphate (CaP). These are collagen type I, a mussel-protein-inspired adhesive consisting of PEG substituted with catechol groups, cPEG
C Nieboer et al.
Journal of the American Academy of Dermatology, 20(4), 601-608 (1989-04-01)
For the past two decades fumaric acid (FA) therapy has become an increasingly popular treatment in Western Europe for psoriasis. FA therapy originally was developed by Schweckendiek and subsequently standardized by Schäfer. Schäfer's fumaric acid compound therapy (FACT) consists of
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