Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

W255807

Sigma-Aldrich

2,3-Hexanedione

≥95%, FG

Synonym(s):

Acetyl butyryl

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
CH3CH2CH2COCOCH3
CAS Number:
3848-24-6
Molecular Weight:
114.14
FEMA Number:
2558
Beilstein/REAXYS Number:
1699896
EC Number:
223-350-8
Council of Europe no.:
152
MDL number:
MFCD00009398
UNSPSC Code:
12164502
PubChem Substance ID:
24901146
Flavis number:
7.018
NACRES:
NA.21
organoleptic:
butter; caramel; creamy; oily; sweet
grade:
FG
Fragrance grade
Halal
Kosher
biological source:
synthetic
agency:
follows IFRA guidelines
food allergen:
no known allergens
Pricing and availability is not currently available.

biological source

synthetic

Quality Level

400

grade

FG
Fragrance grade
Halal
Kosher

agency

follows IFRA guidelines

reg. compliance

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 117
FDA 21 CFR 172.515

vapor density

3.9 (vs air)

vapor pressure

10 mmHg ( 20 °C)

assay

≥95%

refractive index

n20/D 1.412 (lit.)

bp

128 °C (lit.)

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
GF73271280GF70223408GF18083178
Gold tube, 10mm, outside diameter 0.15mm, inside diameter 0.05mm, wall thickness 0.05mm, as drawn, 99.95%

GF10186174

Gold

Gold tube, 100mm, outside diameter 0.3mm, inside diameter 0.2mm, wall thickness 0.05mm, as drawn, 99.95%

GF73271280

Gold

Gold tube, 50mm, outside diameter 1.0mm, inside diameter 0.7mm, wall thickness 0.15mm, as drawn, 99.95%

GF70223408

Gold

Gold tube, 50mm, outside diameter 1.60mm, inside diameter 0.6mm, wall thickness 0.5mm, as drawn, 99.95%

GF18083178

Gold

manufacturer/tradename

Goodfellow 101-861-74

manufacturer/tradename

Goodfellow 732-712-80

manufacturer/tradename

Goodfellow 702-234-08

manufacturer/tradename

Goodfellow 180-831-78

assay

≥99.95%

assay

99.95%

assay

99.95%

assay

99.95%

form

tubes

form

tubes

form

tubes

form

tubes

mp

1063 °C (lit.)

mp

1063 °C (lit.)

mp

1063 °C (lit.)

mp

1063 °C (lit.)

bp

2808 °C (lit.)

bp

2808 °C (lit.)

bp

2808 °C (lit.)

bp

2808 °C (lit.)

resistivity

2.05 μΩ-cm, 0°C

resistivity

2.05 μΩ-cm, 0°C

resistivity

2.05 μΩ-cm, 0°C

resistivity

2.05 μΩ-cm, 0°C

General description

2,3-Hexanedione is a diketone commercially used in food and fragrance industries to get a buttery-cheesy taste in different foodstuffs and fragrances. It is naturally found in coffee, beer, and fermented soya beans.[1][2]

Application


  • Volatile organic compounds of the soil bacterium Bacillus halotolerans suppress pathogens and elicit defense-responsive genes in plants.: This research unveils how volatile organic compounds from Bacillus halotolerans, including 2,3-Hexanedione, can suppress plant pathogens and trigger defense genes. This finding could lead to natural plant protection strategies and enhance agricultural productivity (Rana et al., 2024).

pictograms

FlameHealth hazard
GHS02,GHS08

signalword

Warning

hcodes

H226,H373

Hazard Classifications

Flam. Liq. 3 - STOT RE 2 Inhalation

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

82.4 °F - closed cup

flash_point_c

28 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

  • Specification Sheet

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    SHBN7755
    SHBN6781
    SHBN3088
    SHBL8781
    SHBL7712

    Don't see the Right Version?

    If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

    Search for a COA

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Molecular mechanism of hexane neuropathy: significant differences in pharmacokinetics between 2.3-, 2.4-, and 2.5-hexanedione.
    K Iwasaki et al.
    Industrial health, 22(3), 177-187 (1984-01-01)
    Thomas R Zilz et al.
    Toxicology, 231(2-3), 210-214 (2007-01-19)
    The potential cytotoxicity of two hexanedione food additives (2,3 and 3,4 isomers) was evaluated in comparison with the neurotoxic hexane metabolite 2,5-hexanedione in the human SK-N-SH neuroblastoma line using the MTT assay to indicate mitochondrial dehydrogenase activity and flow cytometry
    Michael D Coleman et al.
    Basic & clinical pharmacology & toxicology, 102(1), 25-29 (2007-11-02)
    The effects of the alpha-diketone derivatives 2,3- and 3,4-hexanediones were investigated in three non-neuronal cell lines (MCF7, HepG(2) and CaCo-2) as well as in the neuroblastoma line, SH-SY5Y. The MTT reduction assay was employed to determine the necrotic effects of
    Emerson S Lacey et al.
    Journal of chemical ecology, 30(8), 1493-1507 (2004-11-13)
    This is the first fully verified report of an aggregation pheromone produced by a cerambycid beetle species. Field bioassays with adult Neoclytus acuminatus acuminatus (F.) (Coleoptera: Cerambycidae) revealed that males produce a pheromone that attracts both sexes. Extracts of odors
    F K Zimmermann et al.
    Mutation research, 270(2), 151-166 (1992-11-16)
    Induction of mitotic chromosome loss could be demonstrated for the dialdehyde glyoxal, the diketones 2,3-butanedione and 2,3-hexanedione, ethyl and methyl carbamate, ethyl acrylate, dibromoacetonitrile, 2-hydroxypropionitrile and formaldehyde, but only when they were combined with subacute concentrations of propionitrile, which is
    View All Related Papers

    Articles

    A World Without Fragrance? – What going fragrance-free really means

    It seems that more and more consumers are demanding fragrance-free products, be it for household cleaning or personal care. Some believe that in doing so, they are purchasing a more natural product.

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service